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  • Homeostasis - Animation

    Homeostasis

    Animation

  • Homeostasis - Animation

    Homeostasis is a state of balance inside the body, where the body systems work together to keep it functioning normally. The endocrine system keeps this internal balancing act going by releasing chemicals called hormones. The release of the hormones is controlled by negative feedback mechanisms. A negative feedback mechanism works something like a thermostat in your home. A thermostat helps maintain a constant temperature. Think of that as the normal range. When the temperature rises beyond the normal range, the thermostat turns on the air conditioner. Eventually the air conditioner restores the temperature to the normal range. That’s negative feedback. It starts with a normal range, goes beyond the normal range, and then back to normal again. Now, let’s look at how this mechanism works in the body. One example is how the endocrine system controls the amount of sugar in the bloodstream. Insulin is a hormone secreted by the pancreas that maintains a normal amount of sugar in the bloodstream. Shortly after eating a candy bar, tiny sugar molecules enter the bloodstream raising the blood sugar levels. In response, the pancreas secretes the insulin into the bloodstream. Now, the sugar molecules move out of the bloodstream and into the cells of the skeletal muscles, fat and liver. In turn, the blood sugar levels return to normal. That’s how a negative feedback mechanism works to maintain the body’s internal balance.

  • Type 2 diabetes - Animation

    Type 2 diabetes

    Animation

  • Type 2 diabetes - Animation

    Over the past several years, our collective diets have grown unhealthier, and our waistlines have expanded as a result. Doing so, we're putting ourselves at risk for a number of diseases, including type 2 diabetes. Diabetes is serious stuff, if it's not treated, it can lead to some pretty dangerous complications, including nerve and kidney damage. The good news is you can often avoid type 2 diabetes and its complications. You need sugar, or glucose, to keep your body running. Normally when you eat, your pancreas releases a hormone called insulin, which moves the sugar from food out of your blood and into your cells, where it can either be used for energy, or stored. But if you have type 2 diabetes, this system doesn't work as well as it should, in part because your cells have a harder time responding to insulin. As a result, sugar builds up in your blood. Why is that a problem? Well, that excess sugar can damage organs like your eyes and kidneys, and it can lead to complications like nerve damage and heart disease. Diabetes complications could leave you blind, lead to amputation of your toes or feet, and maybe even kill you. You can help prevent diabetes complications by keeping good control over your blood sugar, but first you need to know that you have type 2 diabetes. Sometimes it can be hard to tell because you may not have any symptoms at first. Being very thirsty, tired, or having to go to the bathroom a lot may be pretty good clues that you might have developed diabetes. Blurry vision might also be a clue. Your doctor can confirm it with a blood test. Once you know that you have diabetes, it's your job to keep it under control. You'll need to check your blood sugar at home and talk to your doctor about how to lower it with diet, exercise, and possibly medicine. To avoid serious complications, you'll need to see not just one doctor, but a team of health care professionals. That includes a podiatrist to check your feet, an ophthalmologist to check your eyes, and a dentist for cleanings and exams. Because type 2 diabetes increases your risk for heart disease, you'll also need to see your primary care doctor regularly to have your blood pressure, cholesterol, and triglycerides checked, and to make sure your kidneys are working as well as they should. Like any other disease, it's better to avoid getting type 2 diabetes then to have to treat it. If you're at risk because you're overweight or over age 45, ask your doctor for a blood sugar test at your next check-up. If you have already developed diabetes, you can help avoid complications by staying on top of your health, checking your blood sugars, eating a healthy diet, exercising, and seeing all of your specialists on schedule. Make your doctor a partner in your care. Call right away if you have any problems, like numbness or tingling in your legs or feet, blurry vision, extreme thirst, weakness, or fatigue.

  • Type 1 diabetes - Animation

    Type 1 diabetes

    Animation

  • Type 1 diabetes - Animation

    Your body is a fuel-burning machine, and the main fuel it burns is sugar, also known as glucose. In people who have diabetes, though, the body doesn't effectively store and use sugar for energy. As a result, sugar builds up in the blood, where it can lead to serious problems like blindness and nerve damage. Let's talk about a kind of diabetes known as type 1 diabetes. Unlike type 2 diabetes, which is often caused by obesity, type 1 diabetes is an autoimmune disease. That means your immune system, which normally protects your body, turns against you. In this case, the immune system attacks the cells in the pancreas that produce insulin. Insulin is a hormone that moves sugar into cells. There it's stored until your body needs it for energy. Without enough insulin, sugar can't move into your cells, so it builds up in your bloodstream. How do you know that you have Type 1 diabetes?The first signs are usually that you feel very thirsty or tired. You may lose weight without having planned to, or feel numbness or tingling in your hands or feet. If your blood sugar has already gotten very high, your body can't use sugar for energy, so it uses fat instead. This leads to a condition called diabetic ketoacidosis. Your breath will smell fruity, like you've just eaten a fruit salad. Your breathing will get faster, and you may feel sick to your stomach. Your doctor will test your blood sugar level to find out if you have type 1 diabetes. The test may be done when you haven't eaten anything, this is called a fasting blood glucose test. When you have type 1 diabetes, you need to take insulin to replace what your body isn't making. Insulin is only available as an injection, so you'll have to learn how to give yourself a shot each day or wear a pump that delivers insulin to your body continuously. Managing diabetes also means watching your diet so you don't get too much or too little sugar at once. You also need to check your blood sugar levels regularly, and keep track of them over time. Type 1 diabetes is a lifelong disease, but it's one you can control, and live with. The key to staying healthy with diabetes is partnering with your team of doctors. Test your blood sugar at home, and have your doctor check your A1c levels at least every 3 to 6 months. This test shows how well you're controlling your blood sugar over time. Also visit your doctor for regular cholesterol, blood pressure, and kidney tests. See an eye doctor at least once a year, and a dentist every 6 months. Also check your feet every day for skin sores that you might not be able to feel because of nerve damage. And see a podiatrist or your regular doctor for a foot exam twice a year. If you're having any symptoms like fatigue, frequent urination, blurred vision, foot sores, numbness or tingling, or a fast heartbeat, call your doctor right away.

  • Seizures - Animation

    Seizures

    Animation

  • Seizures - Animation

    Having a brain seizure can be a terrifying experience. If you have a seizure, there was a problem with too much uncoordinated electrical activity in your brain. In general, a seizure is when too many of your brain cells become excited at the same time. There are two different types of seizures, generalized and partial. With a generalized seizure, your brain has abnormal electrical activity on both sides of your brain. Partial seizures happen when electrical activity surges in one part of your brain. Seizures can happen for many reasons:It may be from high levels of salt or sugar in your blood; brain injury from a stroke or head injury brain problems you are born with or perhaps a brain tumor. Dementia, such as Alzheimer's disease, high fever or illnesses or infections that hurt your brain. Illegal drug use or withdrawal from alcohol or drug use can cause seizures as well. So, what are the signs that someone is having a seizure?Some people with seizures may have simple staring spells, while others have violent, uncontrollable shaking and loss of consciousness. Some people will see flashing lights, others may hallucinate. Some people may have strange sensations, such as tingling, smelling an odor that isn't really there, or emotional changes. Most people who have a seizure for the first time will go to the emergency room. The doctor will do tests to rule out medical causes, such as a stroke. You may have blood tests, CT or MRI scans of your head, or a spinal tap. Treatment depends on the cause of your seizure. For example, if a seizure was caused by fever, treatment will focus on bringing the fever down. Your doctor may send you home with some medicines to help you avoid having more seizures if there is reason to think you are at continued risk of seizures. You should get plenty of sleep and try to keep as regular a schedule as possible, and try to avoid too much stress. Most people with seizures can have a very active lifestyle. Plan ahead for the possible dangers of a certain activity. Avoid any activity where loss of consciousness would be dangerous until it is clear that seizures are unlikely to occur again.

  • Low blood sugar symptoms

    Low blood sugar symptoms

    Symptoms such as weakness, feeling tired, shaking, sweating, headache, hunger, nervousness and irritability are signs that a person's blood sugar is getting dangerously low. A person showing any of these symptoms should check their blood sugar. If the level is low (70 mg/dL), a sugar-containing food should be eaten right away.

    Low blood sugar symptoms

    illustration

  • Fetal blood testing

    Fetal blood testing

    Fetal blood testing is performed during labor to test the blood pH of the baby which can determine its well-being during delivery. A small puncture is made in the scalp and fetal blood droplets are collected in a thin glass tube. Testing the scalp pH can help your doctor decide if your fetus is getting enough oxygen during labor. This helps determine if your baby is healthy enough to continue labor, or if a forceps delivery or cesarean delivery might be the best route of birth.

    Fetal blood testing

    illustration

  • Newborn screening testing

    Newborn screening testing

    Blood is routinely drawn from newborn infants for testing. Blood is obtained by a heel stick and collected on a special blotter paper. Routine testing usually includes phenylketonuria, thyroid function, hemoglobin S (sickle cell disease), and may test for other disorders. Newborn screening programs vary from state to state. Testing can be tailored to the local population, determining what routine testing should be done.

    Newborn screening testing

    illustration

  • Homeostasis - Animation

    Homeostasis

    Animation

  • Homeostasis - Animation

    Homeostasis is a state of balance inside the body, where the body systems work together to keep it functioning normally. The endocrine system keeps this internal balancing act going by releasing chemicals called hormones. The release of the hormones is controlled by negative feedback mechanisms. A negative feedback mechanism works something like a thermostat in your home. A thermostat helps maintain a constant temperature. Think of that as the normal range. When the temperature rises beyond the normal range, the thermostat turns on the air conditioner. Eventually the air conditioner restores the temperature to the normal range. That’s negative feedback. It starts with a normal range, goes beyond the normal range, and then back to normal again. Now, let’s look at how this mechanism works in the body. One example is how the endocrine system controls the amount of sugar in the bloodstream. Insulin is a hormone secreted by the pancreas that maintains a normal amount of sugar in the bloodstream. Shortly after eating a candy bar, tiny sugar molecules enter the bloodstream raising the blood sugar levels. In response, the pancreas secretes the insulin into the bloodstream. Now, the sugar molecules move out of the bloodstream and into the cells of the skeletal muscles, fat and liver. In turn, the blood sugar levels return to normal. That’s how a negative feedback mechanism works to maintain the body’s internal balance.

  • Type 2 diabetes - Animation

    Type 2 diabetes

    Animation

  • Type 2 diabetes - Animation

    Over the past several years, our collective diets have grown unhealthier, and our waistlines have expanded as a result. Doing so, we're putting ourselves at risk for a number of diseases, including type 2 diabetes. Diabetes is serious stuff, if it's not treated, it can lead to some pretty dangerous complications, including nerve and kidney damage. The good news is you can often avoid type 2 diabetes and its complications. You need sugar, or glucose, to keep your body running. Normally when you eat, your pancreas releases a hormone called insulin, which moves the sugar from food out of your blood and into your cells, where it can either be used for energy, or stored. But if you have type 2 diabetes, this system doesn't work as well as it should, in part because your cells have a harder time responding to insulin. As a result, sugar builds up in your blood. Why is that a problem? Well, that excess sugar can damage organs like your eyes and kidneys, and it can lead to complications like nerve damage and heart disease. Diabetes complications could leave you blind, lead to amputation of your toes or feet, and maybe even kill you. You can help prevent diabetes complications by keeping good control over your blood sugar, but first you need to know that you have type 2 diabetes. Sometimes it can be hard to tell because you may not have any symptoms at first. Being very thirsty, tired, or having to go to the bathroom a lot may be pretty good clues that you might have developed diabetes. Blurry vision might also be a clue. Your doctor can confirm it with a blood test. Once you know that you have diabetes, it's your job to keep it under control. You'll need to check your blood sugar at home and talk to your doctor about how to lower it with diet, exercise, and possibly medicine. To avoid serious complications, you'll need to see not just one doctor, but a team of health care professionals. That includes a podiatrist to check your feet, an ophthalmologist to check your eyes, and a dentist for cleanings and exams. Because type 2 diabetes increases your risk for heart disease, you'll also need to see your primary care doctor regularly to have your blood pressure, cholesterol, and triglycerides checked, and to make sure your kidneys are working as well as they should. Like any other disease, it's better to avoid getting type 2 diabetes then to have to treat it. If you're at risk because you're overweight or over age 45, ask your doctor for a blood sugar test at your next check-up. If you have already developed diabetes, you can help avoid complications by staying on top of your health, checking your blood sugars, eating a healthy diet, exercising, and seeing all of your specialists on schedule. Make your doctor a partner in your care. Call right away if you have any problems, like numbness or tingling in your legs or feet, blurry vision, extreme thirst, weakness, or fatigue.

  • Type 1 diabetes - Animation

    Type 1 diabetes

    Animation

  • Type 1 diabetes - Animation

    Your body is a fuel-burning machine, and the main fuel it burns is sugar, also known as glucose. In people who have diabetes, though, the body doesn't effectively store and use sugar for energy. As a result, sugar builds up in the blood, where it can lead to serious problems like blindness and nerve damage. Let's talk about a kind of diabetes known as type 1 diabetes. Unlike type 2 diabetes, which is often caused by obesity, type 1 diabetes is an autoimmune disease. That means your immune system, which normally protects your body, turns against you. In this case, the immune system attacks the cells in the pancreas that produce insulin. Insulin is a hormone that moves sugar into cells. There it's stored until your body needs it for energy. Without enough insulin, sugar can't move into your cells, so it builds up in your bloodstream. How do you know that you have Type 1 diabetes?The first signs are usually that you feel very thirsty or tired. You may lose weight without having planned to, or feel numbness or tingling in your hands or feet. If your blood sugar has already gotten very high, your body can't use sugar for energy, so it uses fat instead. This leads to a condition called diabetic ketoacidosis. Your breath will smell fruity, like you've just eaten a fruit salad. Your breathing will get faster, and you may feel sick to your stomach. Your doctor will test your blood sugar level to find out if you have type 1 diabetes. The test may be done when you haven't eaten anything, this is called a fasting blood glucose test. When you have type 1 diabetes, you need to take insulin to replace what your body isn't making. Insulin is only available as an injection, so you'll have to learn how to give yourself a shot each day or wear a pump that delivers insulin to your body continuously. Managing diabetes also means watching your diet so you don't get too much or too little sugar at once. You also need to check your blood sugar levels regularly, and keep track of them over time. Type 1 diabetes is a lifelong disease, but it's one you can control, and live with. The key to staying healthy with diabetes is partnering with your team of doctors. Test your blood sugar at home, and have your doctor check your A1c levels at least every 3 to 6 months. This test shows how well you're controlling your blood sugar over time. Also visit your doctor for regular cholesterol, blood pressure, and kidney tests. See an eye doctor at least once a year, and a dentist every 6 months. Also check your feet every day for skin sores that you might not be able to feel because of nerve damage. And see a podiatrist or your regular doctor for a foot exam twice a year. If you're having any symptoms like fatigue, frequent urination, blurred vision, foot sores, numbness or tingling, or a fast heartbeat, call your doctor right away.

  • Seizures - Animation

    Seizures

    Animation

  • Seizures - Animation

    Having a brain seizure can be a terrifying experience. If you have a seizure, there was a problem with too much uncoordinated electrical activity in your brain. In general, a seizure is when too many of your brain cells become excited at the same time. There are two different types of seizures, generalized and partial. With a generalized seizure, your brain has abnormal electrical activity on both sides of your brain. Partial seizures happen when electrical activity surges in one part of your brain. Seizures can happen for many reasons:It may be from high levels of salt or sugar in your blood; brain injury from a stroke or head injury brain problems you are born with or perhaps a brain tumor. Dementia, such as Alzheimer's disease, high fever or illnesses or infections that hurt your brain. Illegal drug use or withdrawal from alcohol or drug use can cause seizures as well. So, what are the signs that someone is having a seizure?Some people with seizures may have simple staring spells, while others have violent, uncontrollable shaking and loss of consciousness. Some people will see flashing lights, others may hallucinate. Some people may have strange sensations, such as tingling, smelling an odor that isn't really there, or emotional changes. Most people who have a seizure for the first time will go to the emergency room. The doctor will do tests to rule out medical causes, such as a stroke. You may have blood tests, CT or MRI scans of your head, or a spinal tap. Treatment depends on the cause of your seizure. For example, if a seizure was caused by fever, treatment will focus on bringing the fever down. Your doctor may send you home with some medicines to help you avoid having more seizures if there is reason to think you are at continued risk of seizures. You should get plenty of sleep and try to keep as regular a schedule as possible, and try to avoid too much stress. Most people with seizures can have a very active lifestyle. Plan ahead for the possible dangers of a certain activity. Avoid any activity where loss of consciousness would be dangerous until it is clear that seizures are unlikely to occur again.

  • Low blood sugar symptoms

    Low blood sugar symptoms

    Symptoms such as weakness, feeling tired, shaking, sweating, headache, hunger, nervousness and irritability are signs that a person's blood sugar is getting dangerously low. A person showing any of these symptoms should check their blood sugar. If the level is low (70 mg/dL), a sugar-containing food should be eaten right away.

    Low blood sugar symptoms

    illustration

  • Fetal blood testing

    Fetal blood testing

    Fetal blood testing is performed during labor to test the blood pH of the baby which can determine its well-being during delivery. A small puncture is made in the scalp and fetal blood droplets are collected in a thin glass tube. Testing the scalp pH can help your doctor decide if your fetus is getting enough oxygen during labor. This helps determine if your baby is healthy enough to continue labor, or if a forceps delivery or cesarean delivery might be the best route of birth.

    Fetal blood testing

    illustration

  • Newborn screening testing

    Newborn screening testing

    Blood is routinely drawn from newborn infants for testing. Blood is obtained by a heel stick and collected on a special blotter paper. Routine testing usually includes phenylketonuria, thyroid function, hemoglobin S (sickle cell disease), and may test for other disorders. Newborn screening programs vary from state to state. Testing can be tailored to the local population, determining what routine testing should be done.

    Newborn screening testing

    illustration

Review Date: 2/28/2024

Reviewed By: Sandeep K. Dhaliwal, MD, board-certified in Diabetes, Endocrinology, and Metabolism, Springfield, VA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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